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Gastrointestinal conditions such as pernicious anemia (autoimmune destruction of gastric parietal cells), Crohn's disease, celiac disease, and prior gastric or ileal surgery significantly impair absorption

[53] In two of these (NCT03954834 and NCT04039503), participants were randomly assigned to receive either tirzepatide or placebo injection weekly

How is Zepbound supplied 16.1 How Supplied ZEPBOUND (tirzepatide) is a clear, colorless to slightly yellow solution available in cartons containing 4 pre-filled single-dose pens, 1 single-dose vial, 4 single-dose vials, 1 multi-dose vial, or 1 single-patient-use KwikPen as follows: 16.2 Storage and Handling Do not freeze ZEPBOUND

This enhanced synchronization probably results from phase-locked action-potential firing within the motor cortexbasal ganglia circuit 65